Hello Commanders,
I know there are some out there using the X52/X52 pro on Windows 10.
I just happen to be checking if there is a new release since the last beta I installed (which after upgrading to win10, the beta was an improvement on the older drivers) and yes, there is a new release today.
Check it out here X52 Win10 and here X52 Pro Win10
They have both 32bit and 64bit, although I expect no one is interested in 32bit after the horizons will be 64bit only announcement.
Fly Safe.