Another issue with the Python is its relatively weak shields. The max shields you can have on the Python is around 855, which is just barely above the Vulture's 826 (excluding any engineer mods).
Of course, the Python can more easily boost its shields, unlike the Vulture, and the Python can stack quite a few SCBs.
But for such a large and slow ship (meaning an easy target for Pulse Accelerators and other large/huge weapons) those shields are a bit on the weak side.
Still, I like the Python. But I get the feeling that your overall success in RES/CZ will be better with the Vulture.