That's what I was doing in BD+28 413, core mining in a Python. It was LFT 65 I went to yesterday and I tried some Tritium mining in a Conda but I wasn't thrilled so won't go back, just wanted to see what all the fuss was about. I think Python is king for core mining, boring and predictable but king.
I don't think laser mining LTD (or Painite) is better than core mining VO but I also don't think VO is the best choice either. However, I do think, "yes you should try it out" so you have some valid experience to form your own opinions.